SNX3 drives maturation of Borrelia phagosomes by forming a hub for PI(3)P, Rab5a, and galectin-9
نویسندگان
چکیده
منابع مشابه
[Galectin-9 induces maturation of human monocyte-derived dendritic cells].
We investigated the role of galectin-9 (Gal-9) in maturation of dendritic cells (DC). Culture of immature DCs with exogenous Gal-9 markedly increased the surface expression of CD40, CD54, CD80, CD83, CD86, and HLA-DR in a concentration-dependent manner, although Gal-9 had no effect on differentiation of human monocytes into immature DCs. Gal-9-treated DCs secreted IL-12 but not IL-10, and they ...
متن کاملP REPARATION OF A NEW MEDIUM FOR IN VITRO CULTURE OF BORRELIA MICROTTI AND BORRELIA PERSICA
Borrelia microtti and Borrelia persica are two Iranian strains of spirochetes whose vectors are Ornithodorous tholozani and Ornithodorous erraticus which are responsible for relapsing fever. BSK medium has been used for in vitro culture of other strains of borrelia, although the two mentioned strains could not be successfully cultured in it. We have modified BSK medium by using guinea pig ...
متن کاملIdentification of an immune-regulated phagosomal Rab cascade in macrophages
Interferon-γ (IFN-γ) has been shown to regulate phagosome trafficking and function in macrophages, but the molecular mechanisms involved are poorly understood. Here, we identify Rab20 as part of the machinery by which IFN-γ controls phagosome maturation. We found that IFN-γ stimulates the association of Rab20 with early phagosomes in macrophages. By using imaging of single phagosomes in live ce...
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تحقیق حاضر گزارشی است از تحلیل بخش مقدمه دو دسته از مقالات که عبارتند از: 11 مقاله از دو نویسنده دوزبانه فارسی زبان, که شامل مقدمه 4 مقاله به زبان انگلیسی و چاپ شده در مجلات بین المللی, مقدمه 3 مقاله به زبان انگلیسی و 4 مقاله به زبان فارسی چاپ شده در مجلات داخلی می شود؛ و 12 مقاله از محققان خارجی که در مجله applied linguistics به چاپ رسیده است. مبنای تئوری این تحلیل ها نظریه سوئلز (1990) یا هما...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2019
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.201812106